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Original Article
01 (
04
); 025-028
doi:
10.1055/s-0038-1656491

Impact of Comorbidities on Quality Of Life in Breast Cancer Patients

MD resident, Department of Radiation Oncology, Nizam’s Institute of Medical Sciences, Hyderabad
Associate Professor and HOD, Department of Radiation Oncology, Nizam’s Institute of Medical Sciences, Hyderabad
Assistant Professor, Department of Radiation Oncology, Nizam’s Institute of Medical Sciences, Hyderabad
MD resident, Department of Radiation Oncology, Nizam’s Institute of Medical Sciences, Hyderabad
Senior Resident, Department of Radiation Oncology, Nizam’s Institute of Medical Sciences, Hyderabad
Address for correspondence dr_monica11@yahoo.com
Licence
This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Disclaimer:
This article was originally published by Thieme Medical and Scientific Publishers Private Ltd. and was migrated to Scientific Scholar after the change of Publisher; therefore Scientific Scholar has no control over the quality or content of this article.

Abstract

Abstract

Introduction: Comorbidities are common among cancer patients and with an aging population are becoming more prevalent. These can potentially affect the stage at diagnosis, treatment and outcomes of people with cancer. Despite the intimate relationship between comorbidity and cancer, there is limited consensus on how to record, interpret or manage comorbidities in the context of cancer. Addressing the impact of comorbid conditions in cancer patients warrants improvement in the evidence base from which to make treatment decisions for those with comorbidities.

Methods: In this prospective study, 64 patients with breast cancer, underwent QOL assessment using FACT –B questionnaire at three time points- pre-radiation and three and six months post radiation.

Results: 29(46%) patients had comorbidities of which 23 (35%) had cardiovascular comorbidities and 6 had other comorbidities. The co-morbidities were negatively associated with multiple domains of quality of life, including physical functioning, general health, bodily pain. Patients with diabetes and hypertension had significantly lower scores in physical functioning in comparison to patients without diabetes and hypertension, but improved after treatment. In majority of patients the overall scores were less in patients with co-morbidities compared to patients without any co-morbidity.

Conclusion: Comorbidities can significantly affect the quality of life in patients with comorbidities. Hence greater research into the QOL issues for better patient care and symptom management especially during the transitioning phase from active care to follow up will help clinicians improve the quality of care and interdisciplinary co-ordination.

Keywords

Quality of life
co-morbidities in breast cancer patients
impact of comorbidities

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